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KMID : 1035220160080010039
Korean Journal of Neuromuscular Disorders
2016 Volume.8 No. 1 p.39 ~ p.42
Tacrolimus for Myasthenia Gravis
Kim Yool-Hee

Shin Ha-Young
Abstract
Myasthenia gravis is an autoimmune disorder affecting neuromuscular junction. Corticosteroid and other immunosuppressive agents are used for the treatment of myasthenia gravis. Tacrolimus may also have a potential role in long-term supression of the immune system. There are limited but promising data to suggest beneficial effects of tacrolimus to control myasthenia gravis and to reduce corticosteroid burden. To date, the largest randomised controlled trial could not demonstrate significant differences in their primary endpoint. Therefore, additional well designed and high quality studies are necessary to determine the effects of tacrolimus on myasthenia gravis.
KEYWORD
Myasthenia gravis, Tacrolimus, Immunosuppressants
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